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methicillin susceptible staphylococcus aureus  (ATCC)


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    ATCC methicillin susceptible staphylococcus aureus
    Methicillin Susceptible Staphylococcus Aureus, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 33254 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/methicillin+susceptible+staphylococcus+aureus/pm41961440-48-20-25?v=ATCC
    Average 99 stars, based on 33254 article reviews
    methicillin susceptible staphylococcus aureus - by Bioz Stars, 2026-07
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    (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus <t>ATCC</t> <t>9144</t> and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).
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    (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus <t>ATCC</t> <t>9144</t> and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).
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    (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus <t>ATCC</t> <t>9144</t> and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).
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    (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus <t>ATCC</t> <t>9144</t> and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).
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    (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus ATCC 9144 and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).

    Journal: Chemical Science

    Article Title: An increased throughput workflow to identify ion transport and membrane lysis agents for antimicrobial discovery

    doi: 10.1039/d5sc09781a

    Figure Lengend Snippet: (a) Results from screening Library 1 in the “catch all” KCl assay using POPC, POPG and POPE/POPG (2 : 1) vesicles, at 10 mol% with respect to lipid. The dotted line represents our cut-off criterion for further analysis (>70% efflux), used to identify the most active SSAs detailed in ; (b) S anion values for the most active SSAs in Library 1 against POPC and POPE/POPG (2 : 1) tested at 10 mol% w.r.t. lipid; (c) heatmaps detailing the percentage of antimicrobial growth inhibition obtained for Library 1 and AT at 100 µM against S. aureus ATCC 9144 and S. aureus NCTC 13616 at 20 hours. Heatmaps display the percent inhibition of either optical density (turbidity or growth), and inhibition of fluorescence (metabolic activity) at 20 hours. All values were blank adjusted and normalised to the positive control for complete inhibition (DMSO + broth, to calibrate 100% inhibition of growth/metabolic activity).

    Article Snippet: However, antimicrobial testing against the methicillin susceptible S. aureus ATCC 9144 strain indicated the opposite trend, while in other strains the two enantiomers performed similarly.

    Techniques: Inhibition, Fluorescence, Activity Assay, Positive Control

    (a) Overlay of 31 P HSQC spectra of phospholipids extracted from S. aureus ATCC 9144 (red) and S. aureus NCTC 13616 (black); (b) differences in total phospholipid composition between S. aureus ATCC 9144 (blue) and S. aureus NCTC 13616 (orange).

    Journal: Chemical Science

    Article Title: An increased throughput workflow to identify ion transport and membrane lysis agents for antimicrobial discovery

    doi: 10.1039/d5sc09781a

    Figure Lengend Snippet: (a) Overlay of 31 P HSQC spectra of phospholipids extracted from S. aureus ATCC 9144 (red) and S. aureus NCTC 13616 (black); (b) differences in total phospholipid composition between S. aureus ATCC 9144 (blue) and S. aureus NCTC 13616 (orange).

    Article Snippet: However, antimicrobial testing against the methicillin susceptible S. aureus ATCC 9144 strain indicated the opposite trend, while in other strains the two enantiomers performed similarly.

    Techniques: